How structural adaptability exists alongside HLA-A2 bias in the human alphabeta TCR repertoire
نویسندگان
چکیده
How structural adaptability exists alongside HLA-A2 bias in the human alphabeta TCR repertoire" (2016).
منابع مشابه
How structural adaptability exists alongside HLA-A2 bias in the human αβ TCR repertoire.
How T-cell receptors (TCRs) can be intrinsically biased toward MHC proteins while simultaneously display the structural adaptability required to engage diverse ligands remains a controversial puzzle. We addressed this by examining αβ TCR sequences and structures for evidence of physicochemical compatibility with MHC proteins. We found that human TCRs are enriched in the capacity to engage a pol...
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